Simultaneous HPTLC determination of strychnine and brucine in strychnos nux-vomica seed
نویسندگان
چکیده
منابع مشابه
Tlc – Spectrophotometric Analysis of Strychnine and Brucine from the Ayurvedic Pills of Nux Vomica
Ayurvedic preparations claim on their label only the quantity of crude drugs and not the quantity of active ingredients present therein. So work was taken up to find the percentage of strychnine and brucine from Ayurvedic pills of Nux vomica powder by TLC spectrophotometric analysis, which study has not been reported earlier. However, the literature survey only revealed the following work.
متن کاملPhytochemical analysis and standardization of Strychnos nux-vomica extract through HPTLC techniques
Phytochemical analysis and standardization of Strychnos nux-vomica extract through HPTLC techniques Dinesh Kumar Patel , Kanika Patel, B. Duraiswamy, S. P. Dhanabal Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi-221005, India. J.S.S. College of Pharmacy, Ooty643 001, India. 3 G.L.A Institute of Pharmaceutical Research, Mathura, India Asian Pacific Journ...
متن کاملA rare case of strychnine poisoning by consumption of Strychnos nux- vomica leaves
Strychnine is one of the oldest poisons known to man. The source of this potent toxin is the Strychnos nux-vomica plant, which actually contains two distinct alkaloidsstrychnine and brucine. Although principally found in the seeds, these alkaloids can be isolated in varying concentrations from virtually all parts of the plant including the bark, leaves and roots[1]. Once consumed, strychnine pr...
متن کاملStrychnos nux-vomica seeds: Pharmacognostical standardization, extraction, and antidiabetic activity
BACKGROUND Strychnos nux-vomica, commonly known as kuchla, contains strychnine and brucine as main constituents. Minor alkaloids present in the seeds are protostrychnine, vomicine, n-oxystrychnine, pseudostrychnine, isostrychnine, chlorogenic acid, and a glycoside. Seeds are used traditionally to treat diabetes, asthma, aphrodisiac and to improve appetite. OBJECTIVE The present study was aime...
متن کاملDevelopment and validation of a TLC-densitometric method for the simultaneous quantitation of strychnine and brucine from Strychnos spp. and its formulations.
A simple, sensitive, and specific thin-layer chromatography densitometric method has been developed for the simultaneous quantitation of strychnine and brucine. These two marker compounds are quantitated in the seeds of Strychnos nux-vomica, Strychnos ignatii, and its formulations. The method involves densitometric evaluation of strychnine and brucine after resolving it by high-performance TLC ...
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ژورنال
عنوان ژورنال: Journal of Pharmacy and Bioallied Sciences
سال: 2012
ISSN: 0975-7406
DOI: 10.4103/0975-7406.94814